Dengue information disease surveillance epidemiology. Dengue knowledge for medical students and physicians. The pdf version will be available on the who searo website. Department of health and human services centers for. Uncertainty in burden estimates, however, challenges policy makers ability to set priorities, allocate resources, and plan for interventions. The dengue vaccine dilemma the lancet infectious diseases. Dengue cannot be spread directly from person to person. Dengue hemorrhagic fever and dengue shock syndrome some patients with dengue fever go on to develop dengue hemorrhagic fever dhf, a severe and sometimes fatal form of the disease. It is estimated that for week 36 of 2016 there have been a total of 8975 cases of dengue, 2081 of which correspond to severe dengue, with 11 deaths. Dengue fever in burkina faso, 2016 pubmed central pmc. Guidelines for dengue fever and dengue haemorrhagic fever.
Dengue hemorrhagic fever is a rare but more severe form of dengue infection that can be fatal if not recognized and treated with supportive care. Dengue and dengue haemorrhagic fever world health organization. Around the time the fever begins to subside usually 37 days after symptom onset, the patient may develop warning signs of severe disease. Cydtdv is a live recombinant tetravalent vaccine based on the yellow fever 17d backbone and is registered as a 3dose vaccine given on a 06. The ethics committee of the national institute of public health project nos.
Dengue classically presents with high fever, headache, body aches, exanthem, and generalized lymphadenopathy. Dengue is a febrile illness caused by a flavivirus transmitted by aedes aegypti or aedes albopictus mosquitoes while taking a blood meal. Dengue fever is a disease caused by one of four related viruses transmitted to humans by the bite of an infected mosquito. Symptoms typically begin three to fourteen days after infection. Dengue is a viral disease transmitted by mosquitoes especially aedes aegypti and is widely distributed throughout the tropics and subtropics. Jul 03, 2018 clinical information and blood samples were collected from patients who visited or were admitted to various clinics or hospitals during junenovember 2016. Dengue fever is common in tropical areas, so take extra precautions if you travel somewhere with this type of. The illness may progress to dengue hemorrhagic fever dhf. Symptoms include fever, headache, muscle and joint pains, and a. In palau, a steep rise in dengue cases was recognized starting in november 2016. Critique of world health organization recommendation of a. Symptoms include a high fever, headaches, joint and muscle pain, vomiting, and a rash. Since the second edition of dengue haemorrhagic fever.
Of 35 serum samples tested by a trioplex test, 19 were confirmed dengue virus denv. Who position paper july 2016 pdf 437kb other tetravalent liveattenuated vaccines are under development in phase iii clinical trials, and other vaccine candidates based on subunit, dna and purified inactivated virus platforms are at earlier stages of clinical development. Dengue disease varies from mild fever to severe conditions of dengue hemorrhagic fever and shock syndrome. Dengue fever in burkina faso, 2016 article pdf available in emerging infectious diseases 241. Dengue viruses are spread to people through the bite of an infected aedes species ae.
Patients should be advised to stay well hydrated and to avoid aspirin acetylsalicylic acid, aspirincontaining drugs, and other nonsteroidal antiinflammatory drugs such as ibuprofen because of their anticoagulant properties. Dengue is a mosquitoborne flavivirus found in tropical and subtropical regions of the world, mostly in urban and semiurban settings. The disease is often diagnosed incorrectly because the symptoms are similar to influenza and other viruses. Symptoms include severe abdominal pain, vomiting, diarrhea, convulsions, bruising, and uncontrolled bleeding. Health experts have known about dengue fever for more than 200 years. The disease is limited primarily to the tropics and. Complications can lead to circulatory system failure and shock, and can be fatal also known as dengue shock syndrome. Journal of chemical and pharmaceutical research, 2016, 83.
The first dengue vaccine, dengvaxia cydtdv by sanofi pasteur, was first licensed in december, 2015, in mexico. A severe form of dengue fever, also called dengue hemorrhagic fever, can cause severe bleeding, a sudden drop in blood pressure shock and death. Mar 12, 2020 dengue is an infection caused by a virus. Although the case numbers returned to a lower level after 2010, the end of 2012 and 20 were marked by a strong increase, which is probably related to several dengue outbreaks in tropical countries. Dengue fever, also known as breakbone fever, is a mosquitoborne infectious tropical disease caused by the dengue virus. Healthrelated quality of life after dengue fever, morelos. Many of the previous economic burden studies for dengue fever were not standardized, making them difficult to compare. Dengue outbreaks occur each year in north queensland following cases imported from overseas.
Dengue fever is a mosquitoborne arthropodborne viral arboviral tropical disease in humans. To better understand dengue epidemiology and clinical characteristics in burkina faso, a fever surveillance study was conducted among patients aged 155 years, who presented with nonmalarial febrile illness at five primary healthcare facilities in ouagadougou, burkina faso from december 2014 to february 2017, encompassing a 3month dengue outbreak in septembernovember 2016. We recruited participants with dengue from inpatient and outpatient facilities in morelos, mexico, during 20162017. Dengue viruses are the causative agents of dengue fever df and dengue hemorrhagic. Dengue fever vaccine the first dengue vaccine, dengvaxia, was made available in mexico in december 2015. Regarding dengue haemorrhagic fever, equivalent to dengue with warning signs and severe dengue, in that same year, a total of 5626 cases were reported. An outbreak of dengue fever occurred in nepal during june to november 2016, with a peak number of. It can cause severe flulike symptoms and in severe cases can be fatal. Dengue begins abruptly after an incubation period of 57 days range, 310 days, and the course follows 3 phases. April 2016 dengue fever surveillance protocol 1 dengue, also known as dengue fever df, dengue hemorrhagic fever dhf, or breakbone fever, is a mosquitoborne viral infection that manifests with fever and may be accompanied by a combination of. Despite the increase of dengue fever cases, there continues to be a lack of economic assessment partly due to the absence of vaccines until recent times.
It is the fastest spreading vectorborne viral disease and is now endemic in over 100 countries, resulting in 40% of the worlds population living in an area at risk for dengue. For those who develop severe dengue, close observation and frequent monitoring in. Dengue virus cannot be transmitted from person to person. European centre for disease prevention and control. Clinical information and blood samples were collected from patients who visited or were admitted to various clinics or hospitals during junenovember 2016. Dengue disease varies from mild fever to severe conditions of dengue hemorrhagic. The who regional office for southeast asia publish dengue. Forty percent of the worlds population, about 3 billion people, live in areas with a risk of dengue. Dengue is transmitted principally by aedes aegypti yellow fever mosquito and aedes albopictus asian tiger mosquito. Febrile patients should avoid mosquito bites to reduce risk of further transmission. The disease can have severe manifestations, including dengue hemorrhagic fever dhf and dengue shock syndrome dss. This live vaccine, which covers all four dengue subtypes, is given to people ages 9 to 45.
We report 1,327 probable cases of dengue in burkina faso in 2016. Dengue fever is a severe, flulike illness that affects infants, young children and adults, but seldom causes death. Infants and young children may have a nonspecific febrile illness with rash. Dengue is often a leading cause of illness in areas. Who position paper july 2016 pdf 437kb other tetravalent liveattenuated vaccines are under development in phase iii clinical trials, and other vaccine candidates based on subunit, dna and purified inactivated virus platforms are. A multicountry study of the economic burden of dengue fever. It has been registered for use in individuals 945 years of age living in endemic areas. Mild dengue fever causes a high fever, rash, and muscle and joint pain. Profile of the 2016 dengue outbreak in nepal bmc research. It is caused by any of the 4 serotypes of dengue virus and is transmitted within humans through female aedes mosquitoes. Dengue fever oregon selected reportable communicable. Causes, prevention and recent advances find, read and cite all the research you need on researchgate. Dengue chapter 4 2020 yellow book travelers health cdc. Although dengue virus infections are usually selflimiting, dengue infection has come up as a public.
Author summary dengue fever has been prevalent in southeast asia and south america. Dengue guidelines for diagnosis, treatment, prevention and control pdf. These may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin rash. Dengue pronounced dengee is a viral disease transmitted to humans by the bite of an infected aedes mosquito, especially aedes aegypti yellow fever mosquito and aedes albopictus tiger mosquito. Fever should be controlled with acetaminophen and tepid sponge baths. Causes, prevention and recent advances find, read and cite all. Feb 16, 2018 dengue denggey fever is a mosquitoborne disease that occurs in tropical and subtropical areas of the world.
Dengue prevention and control in the americas ims dengue in collaboration with its member countries in order to tackle the disease through these six components. Dengue is a viral disease transmitted by some types of mosquitoes. The dengue virus, a member of the genus flavivirus of the family flaviviridae, is an arthropodeborne. Comprehensive guidelines for prevention and control of dengue and dengue haemorrhagic fever vii dengue fever is the fastest emerging arboviral infection spread by aedes mosquitoes with major public health consequences in over 100 tropical and subtropical countries in southeast asia, the western pacific and south and central america. The study all study participants signed informed consent forms. The objective of the bulletin is to disseminate updated information on the current status of dengue fever dengue haemorrhagic fever infection, changing. Dengue fever is common in tropical areas, so take extra precautions if you travel somewhere with this type of climate. There are four dengue virus denv types denv1, denv2, denv3, and denv4, all of which are capable of inducing severe disease dengue hemorrhagic fever dhfdengue shock syndrome dss. It is caused by any of the serotypes of dengue virus and is transmitted within humans through female aedes mosquitoes. A 2016 study estimated nearly 60 million symptomatic dengue cases worldwide every year estimates including asymptomatic cases are at least six times higher, resulting in about 10 000 deaths. Disease symptoms were diagnosed by clinicians and classified as dengue fever df or severe dengue disease sdd based on the who classification who 2009. There are four dengue virus denv types denv1, denv2, denv3, and denv4, all of which are capable of inducing severe disease dengue hemorrhagic fever dhf dengue shock syndrome dss. There is no vaccine or medication that protects against dengue fever.
Jan 01, 2018 dengue fever in burkina faso, 2016 article pdf available in emerging infectious diseases 241. Dengue is common in more than 100 countries around the world. Oct 29, 2016 we report 1,327 probable cases of dengue in burkina faso in 2016. The aedes aegypti mosquito is the primary vector of dengue. Pdf dengue fever in burkina faso, 2016 researchgate.
Dengue fever is an infectious disease carried by mosquitoes and caused by any of four related dengue viruses. It is caused by a flavivirus the same genus as west nile, zika and yellow fever viruses. An estimated 500 000 people with severe dengue require hospitalization each year, and about 2. This disease used to be called breakbone fever because it sometimes causes severe joint and muscle pain that feels like bones are breaking. Dengue or dengue fever is a disease spread to humans by mosquito bites, and is caused by one of four types of dengue viruses. There were 329 cases of dengue fever identified between october. Dengue is the most common mosquitotransmitted viral infectious disease. Dengue is a highly endemic infectious disease of the tropical countries and is rapidly becoming a global burden.
Clinical and epidemiologic characteristics associated with. Prevention and control of dengue by herbal remedies. A total of 1 796 cases of dengue fever were reported in tessy in 2014. The clinical features of dengue fever vary according to the age of the patient. In midapril 2016, the world health organizations whos scientific advisory group of experts on immunization sage recommended that dengueendemic countries consider using sanofi pasteurs chimeric yellow fever dengue vaccine dengvaxia to immunize individuals aged 945 years in populations with high levels of dengue. This acute febrile illness can be a deadly infection in cases of severe manifestation, causing dengue hemorrhagic shock. Dengue prevention and control in the americas imsdengue in collaboration with its member countries in order to tackle the disease through these six components. Dengue is a leading cause of illness and death in tropical and subtropical areas. It is widespread across asia, the pacific, central and southern america and africa where these mosquitoes exist. Pdf on jan 1, 2016, anum jaweria and others published dengue fever. For those who develop severe dengue, close observation and frequent monitoring in an intensive care unit may be required.
Pahowho presents this second edition to countries and territories of the americas at a time when other arboviral diseases chikungunya and zika have been. Dengue fever is a mosquitoborne tropical disease caused by the dengue virus. The objective of the bulletin is to disseminate updated information on the current status of dengue feverdengue haemorrhagic fever infection, changing. Dengue fever is a virus transmitted to humans through bites from the aedes mosquito, a daybiting mosquito.1441 953 1261 635 90 950 1045 1554 1026 934 913 1292 283 801 1116 315 192 1319 1284 842 734 29 1208 1267 789 582 1326 140 324 96